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Niina M Saarinen Selected Research

2,3-bis(3'-hydroxybenzyl)butane-1,4-diol (enterodiol)

7/2007Role of dietary lignans in the reduction of breast cancer risk.
7/2006Genistein alone and in combination with the mammalian lignans enterolactone and enterodiol induce estrogenic effects on bone and uterus in a postmenopausal breast cancer mouse model.
4/2006Sesamin is one of the major precursors of mammalian lignans in sesame seed (Sesamum indicum) as observed in vitro and in rats.
3/2006Mammalian lignans enterolactone and enterodiol, alone and in combination with the isoflavone genistein, do not promote the growth of MCF-7 xenografts in ovariectomized athymic nude mice.

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Niina M Saarinen Research Topics

Disease

15Breast Neoplasms (Breast Cancer)
11/2012 - 08/2002
13Neoplasms (Cancer)
01/2014 - 08/2002
6Body Weight (Weight, Body)
01/2014 - 12/2004
2Prostatic Neoplasms (Prostate Cancer)
01/2014 - 01/2010
1Carcinogenesis
01/2010
1Hepatocellular Carcinoma (Hepatoma)
01/2007
1Neoplasm Metastasis (Metastasis)
01/2007
1Carcinoma (Carcinomatosis)
08/2002

Drug/Important Bio-Agent (IBA)

13LignansIBA
01/2014 - 08/2002
82,3-bis(3'-hydroxybenzyl)butyrolactone (enterolactone)IBA
08/2010 - 08/2002
4Biomarkers (Surrogate Marker)IBA
08/2012 - 07/2007
4Estrogens (Estrogen)FDA Link
08/2010 - 07/2006
4Phytoestrogens (Phytoestrogen)IBA
08/2010 - 03/2006
4IsoflavonesIBA
08/2010 - 03/2006
42,3-bis(3'-hydroxybenzyl)butane-1,4-diol (enterodiol)IBA
07/2007 - 03/2006
3Hormones (Hormone)IBA
11/2012 - 04/2006
3GenisteinIBA
08/2010 - 03/2006
3Soybean Proteins (Soy Protein)IBA
11/2008 - 08/2006
2SteroidsIBA
11/2012 - 01/2007
2Estrogen Receptor betaIBA
11/2008 - 09/2008
2lariciresinolIBA
09/2008 - 12/2004
2hydroxymatairesinolIBA
01/2007 - 12/2004
1StilbenesIBA
01/2014
1CytokinesIBA
11/2012
1TamoxifenFDA LinkGeneric
11/2012
1Interleukin-1 (Interleukin 1)IBA
11/2012
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
08/2010
1Proteins (Proteins, Gene)FDA Link
08/2010
1Estrogen Receptor alphaIBA
11/2008
1Tumor Biomarkers (Tumor Markers)IBA
11/2008
1Estrogen ReceptorsIBA
11/2008
1Cyclin D1IBA
11/2008
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
11/2008
1CarcinogensIBA
09/2008
1anthraceneIBA
09/2008
1secoisolariciresinol diglucosideIBA
01/2008
1TritiumIBA
01/2008
1antineoplaston A10 (A 10)IBA
04/2006
1sesaminIBA
04/2006
1Estradiol (Delestrogen)FDA LinkGeneric
03/2006
1secoisolariciresinolIBA
12/2004
1matairesinolIBA
12/2004

Therapy/Procedure

2Oral Administration
01/2008 - 12/2004
2Subcutaneous Injections
07/2006 - 03/2006
1Plant-Based Diet
01/2014
1Therapeutics
11/2012
1Diet Therapy (Therapy, Diet)
11/2012